A preacher sets out on a mission to make the almighty himself confess his sin of abandoning the world. With his best friend Cassidy, an alcoholic Irish vampire, his love Tulip, a red blooded gun towing Texan, and the power of genesis, an unholy child born from an angel and a devil, Jesse gives up everything to set the world straight with its creator.

Dominic Cooper

Jesse Custer

Ruth Negga

Tulip O'Hare

Joseph Gilgun

Cassidy

Ian Colletti

Eugene 'Arseface' Root

Graham McTavish

Saint of Killers

Pip Torrens

Herr Starr

Tyson Ritter

Humperdoo / Jesus Christ

Noah Taylor

Hitler

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