In 2071, roughly fifty years after an accident with a hyperspace gateway made the Earth almost uninhabitable, humanity has colonized most of the rocky planets and moons of the Solar System. Amid a rising crime rate, the Inter Solar System Police (ISSP) set up a legalized contract system, in which registered bounty hunters, also referred to as "Cowboys", chase criminals and bring them in alive in return for a reward.

Koichi Yamadera

Spike Spiegel / Ein (voice)

Unsho Ishizuka

Jet Black (voice)

Megumi Hayashibara

Faye Valentine (voice)

Aoi Tada

Edward Wong Hau Pepelu Tivruski IV (voice)

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