The story of how one company triggered the worst drug epidemic in American history. Look into the epicenter of America's struggle with opioid addiction, from a distressed Virginia mining community, to the hallways of the DEA, and to the opulence of "one percenter" Big Pharma Manhattan.

Michael Keaton

Samuel Finnix

Peter Sarsgaard

Rick Mountcastle

Michael Stuhlbarg

Richard Sackler

Will Poulter

Billy Cutler

John Hoogenakker

Randy Ramseyer

Kaitlyn Dever

Betsy Mallum

Rosario Dawson

Bridget Meyer

Will Chase

Michael Friedman

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