Seven years have passed after the battle of Teppelin... Humans have since reclaimed the surface of the earth and enjoy an unprecedented period of peace and prosperity. However, humanity's increasing population growth triggers the sudden emergence of an unknown, powerful enemy. The fearsome, manipulative power of the mysterious Anti-Spiral proves too overwhelming for humans to even fight back. When everyone becomes desperate and loses hope, Team Dai-Gurren members reunite to stand up once again!

Tetsuya Kakihara

Simon (voice)

Yukari Fukui

Nia Teppelin (voice)

Marina Inoue

Yoko Littner (voice)

Katsuyuki Konishi

Kamina (voice)

Masaya Onosaka

Leeron Littner (voice)

Mitsuki Saiga

Rossiu Adai (voice)

Nobuyuki Hiyama

Viral (voice)

Shizuka Itoh

Boota (voice) / Darry Adai (voice)

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